2009.09-2013.07 华东理工大学，化学工程系，学士
2013.09-2016.06 华东理工大学，化学工程系，硕士
2016.10-2020.12 荷兰格罗宁根大学，化学反应工程，博士
导师：荷兰工程院院士Hero Jan Heeres/乐军教授
【工作经历】
2021.01-2023.01 荷兰代尔夫特理工大学，过程与能源系，博士后，合作导师：Wiebren de Jong教授
2023.10 至今 华东理工大学，能源化工过程智能制造重点实验室，特聘副研究员
【个人荣誉】
2023上海市海外领军人才
2025国家教育部海外高层次人才
【学术兼职】
中国化工学会会员，中国自动化学会会员，中国系统工程学会会员
ACS期刊《Chem & Bio Engineering》青年编委
【研究方向】
面向资源循环利用、化工过程低碳转型和流程工业智能化需求，长期开展可持续化工、反应工程、过程系统工程与工业人工智能交叉研究：
1. 可持续碳资源转化与绿色化学品、材料
围绕生物质、废塑料及工业固体废弃物等可持续碳资源，研究其定向转化机理、催化反应网络与绿色工艺，开发高值化学品、绿色燃料、可持续单体及聚合物的制备技术。
2. 多相反应-传递耦合建模与过程强化
针对多相催化、酯化、聚合及反应-分离耦合过程，建模研究反应动力学、界面传质和流动行为之间的耦合机制，发展微反应器、界面调控和过程强化方法，实现反应选择性、传递效率及能源利用效率的协同提升。
3. 化工过程机理-数据融合建模与工业人工智能
融合第一性原理、反应-传递动力学、工业数据与机器学习，发展物理约束、可解释和可迁移的化工过程智能模型，用于复杂装置状态预测、软测量、异常识别、性能评估和操作优化。
4. 低碳流程系统设计、数字孪生与智能优化
面向炼油化工、新能源耦合和低碳制造系统，开展全流程模拟、技术经济与生命周期评价、多目标优化、不确定性优化及数字孪生研究，构建连接工艺设计、生产运行和自主决策的智能优化方法与工业软件。
【承担项目】
1. 上海市海外高层次人才项目，2023-2026，主持
2. 国家教育部海外高层次人才项目，2025-2028，主持
3. 国家自然科学基金青年项目C类，2025-2027，主持
4. 国家科技部重大专项子课题，2026-2029，主持
5. 中国石化镇海炼化-大型炼厂虚拟制造平台开发，2021-2025，技术负责
6. 中国石化济南炼化-智能催化裂化优化成套技术研发，2022-2024，技术负责
7. 中国石化上海石油化工研究院-传质强化的多相催化酯化关键技术研究，2024-2026，技术负责
8. 中国石油昆仑工程-2,6-NDC酯化催化剂、酯化反应及重结晶动力学研究，2025-2026，技术负责
9. 中国石油广东石化-延迟焦化数字孪生与优化，2025-2026，项目经理
10. 中国石化工程建设公司-基于数据+机理驱动的炼油装置低成本运行预测模型，2026-2029，项目负责
11. 巴斯夫-水处理智能工厂RO过程智能建模与优化，2026-2027，项目负责
【代表性成果】
以第一/通讯作者在AIChE J，Chem. Eng. J.，Chem. Eng. Sci.，Green Chem., ACS Sust. Chem. Eng. 等化学工程、过程系统工程和可持续化工等领域知名期刊发表论文30余篇，公开/授权国家发明专利20项，登记软件著作权8项。代表性成果如下：
[1] W. Guo, H.C. Bruining, H.J. Heeres*, J. Yue, Efficient synthesis of furfural from xylose over HCl catalyst in slug flow microreactors promoted by NaCl addition, AIChE J. 68(5) (2022) e17606.
[2] J. Long, R. Song, L. Wan, W. Guo*, Two-stage multi-objective stochastic optimization of a wind-solar powered steam and green methanol co-production system, AIChE J. (2026) e70475.
[3] W. Guo, H.J. Heeres, J. Yue*, Continuous synthesis of 5-hydroxymethylfurfural from glucose using a combination of AlCl3 and HCl as catalyst in a biphasic slug flow capillary microreactor, Chem. Eng. J. 381 (2020) 122754.
[4] W. Guo, Z. Zhang, J. Hacking, H.J. Heeres, J. Yue*, Selective fructose dehydration to 5-hydroxymethylfurfural from a fructose-glucose mixture over a sulfuric acid catalyst in a biphasic system: Experimental study and kinetic modelling, Chem. Eng. J. 409 (2021) 128182.
[5] J. Long, J. Zhao, Y. Lin, S. Li, W. Guo*, Multi-period interval optimization of a renewable steam-methanol system for uncertainty-aware industrial decarbonization, Chem. Eng. Sci. 338 (2027) 124986.
[6] S. Ayaz, W. Guo*, K. Wang, M. Hedar, L. Zhao, Z. Xi*, Enhanced Biodiesel Synthesis via Interfacial Mass Transfer Intensification in Pickering Emulsions Using an Amphiphilicity-Engineered β-Zeolite Catalyst, ACS Sustainable Chem. Eng. 13(50) (2025) 21633-21647.
[7] Y. Wang, W. Guo*, J. Yue, H.J. Heeres, L. Zhao, Z. Xi*, Experimental Study on the Synthesis of Biobased Poly(ethylene-2,5-furandicarboxylate) and Kinetic Modeling on the Esterification of 2,5-Furandicarboxylic Acid and Ethylene Glycol, ACS Sustainable Chem. Eng. 13(19) (2025) 7299-7317.
[8] P. Zhao, W. Guo*, Z. Gui, J. Jiang, Z. Zhu, J.-J. Li, L. Zhao, J. Zhou, Z. Xi*, Selective Hydrocracking of Waste Polyolefins toward Gasoline-Range Liquid Fuels via Tandem Catalysis over a Cerium-Promoted Pt/HY Catalyst,ACS Sustainable Chem. Eng. 12(15) (2024) 5738-5752.
[9] W. Guo, E.J.M. Hensen, W. Qi, H.J. Heeres, J. Yue*, Titanium Phosphate Grafted on Mesoporous SBA-15 Silica as a Solid Acid Catalyst for the Synthesis of 5-Hydroxymethylfurfural from Glucose, ACS Sustainable Chem. Eng. 10(31) (2022) 10157-10168.
[10] W. Guo, T. Kortenbach, W. Qi, E. Hensen, H. Jan Heeres, J. Yue*, Selective tandem catalysis for the synthesis of 5-hydroxymethylfurfural from glucose over in-situ phosphated titania catalysts: Insights into structure, bi-functionality and performance in flow microreactors, Appl. Catal., B: Environ. 301 (2022) 120800.
[11] R.M. Abdilla-Santes, W. Guo*, P.C.A. Bruijnincx, J. Yue, P.J. Deuss, H.J. Heeres*, High-Yield 5-Hydroxymethylfurfural Synthesis from Crude Sugar Beet Juice in a Biphasic Microreactor, ChemSusChem 12(18) (2019) 4304-4312.
[12] P. Li, B. Shi, J. Shen, R. Cui, W. Guo*, L. Zhao, Z. Xi*, Phosphotungstic acid immobilized on amino-functionalized TS-1 zeolite as a solid acid catalyst for the synthesis of tributyl citrate, Chin. J. Chem. Eng. 70 (2024) 199-210.
[13] X. Chen, K. Luo, C. Huang, J. Gong, J. Long*, W. Guo*, Hybrid Modeling of Catalytic Cracking Processes Based on the 17-Lump Kinetic Model and Light Gradient Boosting Machine, Energy & Fuels 39(14) (2025) 6942-6956.
[14] B. Wang, K. Luo, X. Chen, K. Deng, J. Long*, W. Guo*, Multi-strategy modeling integrating kinetics mechanism of cracking and pyrolysis and unsupervised dual-stage attention long and short-term memory network, Fuel Process. Technol. 279 (2025) 108349.
[15] W. Guo, H.C. Bruining, H.J. Heeres, J. Yue*, Insights into the reaction network and kinetics of xylose conversion over combined Lewis/Brønsted acid catalysts in a flow microreactor, Green Chem. 25(15) (2023) 5878-5898.
[16] B. Ning, Y. Liu, W. Guo*, C. Cao, J.-J. Li, L. Zhao, Z. Xi*, Integration of Esterification and Distillation for Enhanced Production of Dimethyl 2,6-Naphthalenedicarboxylate: Kinetic Modeling, Process Development, and Multiobjective Optimization, Ind. Eng. Chem. Res. 65(21) (2026) 10602-10621.
