报告:Mercury Emissions Control from Coal-Fired Power Plants and Drug Delivery for Combination Cancer Chemotherapy
发布人: 管理员 发布时间: 2017-10-13 作者: 访问次数: 14

讲座时间:1016(周一)上午 9:30-11:30

讲座地点:实验十六楼106

Title: Mercury Emissions Control from Coal-Fired Power Plants and Drug Delivery for Combination Cancer Chemotherapy

Abstract:

The U.S. Environmental Protection Agency started to regulate mercury emissions virtually from all coal- and oil-fired electric generating utility plants by the Mercury Air Toxics Standards (MATS) rule.Among three different mercury species present in coal combustion flue gas, elemental mercury conversion into oxidized form followed by adsorption or absorption is critical to achieving the very stringent mercury emission limits of 1.2 and 0.015 lbs/TBtu from existing and new coal-fired power plants, respectively.Dr. J-Y Lee’s lab has studied the reaction mechanisms and kinetics for catalytic elemental mercury oxidation, adsorption characteristics of oxidized mercury for sorbent injection, and prediction of sorbent injection.In this presentation, some of the study results from high and low temperature catalysts and chemically-promoted powdered activated carbon sorbent will be highlighted.

  

The use of nanoparticles (NPs) as a vehicle for drug delivery with an application to cancer treatment has been around for nearly three decades.Advances in genomics and emerging insights of cell biology have increased the opportunities for tailor-designed and most effective strategies of drug combinations that can achieve high therapeutic efficacy and thus potentially reducing chemotherapeutic drug dosage. Drug development for a complex disease like cancer is shifting from targeting individual genes or proteins to systems-based signaling networks.From this perspective, combination chemotherapy has great potential for enhancing efficacy in treating cancer by applying multiple drugs with complementary and synergistic mechanisms to block multiple survival pathways in cancerous cells.Dr. Lee’s lab has been studying polymeric nanoparticle-based gene and drug delivery system for maximum therapeutic efficacy with minimal side effects against drug-resistant cancer types.In this presentation, some rational NP design approaches for antibody-guided NP, gene and drug co-delivery NP, and sequential co-delivery NP and their therapeutic impacts on treatment will be discussed.

Bio:

Dr. Joo-Youp Lee is an Associate Professor of Chemical Engineering Program in Chemical Engineering Program of the Department of Chemical and Environmental Engineering at the University of Cincinnati. His research interests lie in the areas of energy and environment and nanobiotechnology.He has published over 50 technical peer-reviewed journal papers, 100 conference papers, 40 technical reports, and 8 patents/invention disclosures.He has research and teaching experiences in transport phenomena, chemical reaction engineering, thermodynamics, and air pollution control from combustion sources.His current research interests lie in catalysis and adsorption for environmental applications and targeted and controlled gene and drug delivery.He is also a recipient of the NSF CAREER award.He has BS, MS, and PhD degrees in Chemical Engineering.He also worked as a chemical process engineer on chemical process simulation, design, optimization, and operation in various gas, refinery, and petrochemical processes.